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pyALRA:单细胞RNA测序低秩零保留逼近的Python实现及其性能优化
本文推荐研究人员开发的pyALRA工具,该Python实现解决了单细胞RNA测序(scRNA-seq)中技术性零值("dropout")的插补问题。通过采用自适应阈值低秩逼近(ALRA)算法,研究证明pyALRA在保持生物学零值的同时,显著提升了计算效率和内存使用率,为Python生态的单细胞分析提供了 ...
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